Postdoc Fellow | Saint Louis University - Military Veterans

Postdoctoral Position in Ion Channels and Membrane Proteins at Saint Louis University A postdoctoral position is available in the lab of Dr. Gucan Dai at the Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine. We are seeking highly motivated candidates with a strong background in biophysics and biochemistry, particularly in the study of ion channe ls or membrane proteins. Expertise in patch - clamp electrophysiology or fluorescence imaging is highly desirable. The Dai lab investigates the fundamental mechanisms of ion channels in excitable membranes using a multidisciplinary approach. Our NIH - funded research integrates structural biology, chemical biology, genetics, fluorescence microscopy, and electrophysiology. The lab is equipped with two cutting - edge patch - clamp electrophysiology/fluorescence imaging systems, including Missouris only frequency - do main fluorescence lifetime imaging microscopy system. Research Focus Areas: Voltage - sensing mechanisms of voltage - gated ion channels These channels are key players in conditions such as chronic pain, cardiac arrhythmias, and epileptic seizures. Trainees will gain hands - on experience with advanced techniques like patch - clamp fluo rometry (PCF), Förster resonance energy transfer (FRET), and the use of fluorescent noncanonical amino acids (ncAAs). Lipid - mediated regulation of ion channels and membrane dynamics This research explores the role of lipids in the regulation of ion channels, with implications for inflammatory and neuropathic pain, Alzheimers disease, epilepsy, and viral infections. Rel evant techniques include whole - cell fluorometry, calcium imaging, TIRF microscopy, and fluorescence lifetime imaging. We highly encourage individuals interested in this position, please apply for the position from the link or contact us at gucan.dai@health.slu.edu .