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Post-Doctoral Associate - Masonic Institute on Biology of Aging and Metabolism - Military Veterans

at HERC- Upper MidWest

Masonic Institute on Biology of Aging and Metabolism - Dr. Ming Xu

Several positions available in the Ming Xu laboratory in the Masonic Institute on the Biology of Aging and Metabolism. Xu's research program focuses on discovering fundamental mechanisms of aging. This laboratory employs novel animal models, primary human cells, and human tissues to investigate the roles and underlying mechanisms of cellular senescence in a variety of age-related conditions including frailty, compromised resilience, Alzheimer's diseases, insulin resistance, bone loss, joint pain, infection, and others.

The Xu lab has sufficient long-term fundings (3R01s, multiple R21s and U54) as well as excellent lab environment. The Xu lab has published a number of studies in various highly impactful journals including Nature Medicine, Cell Metabolism, Nature Aging, PNAS, and Aging Cell. The full publication list can be found at https://scholar.google.com/citations?user=v59W39sAAAAJ&hl=en . The candidates will be working on characterizing the role and underlying of senescent cells in age-related conditions. The candidate will join an exciting research environment in the Department of Biochemistry, Molecular Biology and Biophysics and the newly established Institute on the Biology of Aging and Metabolism at University of Minnesota. The position offers exceptional training in stem cells, aging, age-related diseases, cellular senescence, DNA damage and repair and molecular therapeutics.

90% Laboratory Research
Mouse colony management, functional tests, cell culture, microscopy, immunoblotting, qPCR, drug development, experimental design, data analysis and recording primary data and methods used.

5% Research communication
Critical analysis of the literature, preparing manuscripts, oral presentations and posters.

5% Mentoring
Training graduate, undergraduate and technical staff in theoretical and/or bench science

Required:
PhD in Biochemistry, molecular biology or a related area with specialization in cell signaling pathways or stem cell biology.

Preferred:
Genuine interest in aging research, experience working on transgenic mice, human tissues, single cell RNAseq, and/or senescence. Skilled in rodent experimentation, molecular biology, sequencing, imaging, and bioinformatics. Good verbal and written communication skills, ability to work independently, and an interest in mentoring young scientists.

Minneapolis, MN

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