Researcher 2 - Vascular and Brain Aging - Military Veterans
at HERC- Upper MidWest
This position is full time, on site.
Comp range - $25.75 - 29.00/hr
Job description:
How lipids and lipoproteins contribute to vascular and brain aging, and Alzheimer's disease (AD) is unclear. We have a Researcher 2 position immediately available in the lab of Danni Li (Department of Lab Medicine and Pathology, University of Minnesota) to investigate lipids and lipoproteins in two important AD research projects funded by the National Institute on Aging.
We will conduct a large-scale analysis of already-collected blood samples from older adults to examine plasma components known as lipoproteins. This study will uncover previously unknown associations of the proteins and lipids found within plasma lipoproteins with AD development and progression, allowing us to identify new AD biomarkers related to the vascular system for further strategy development to prevent or slow the progression of AD or AD-related dementias. Inheritance of the apolipoprotein (APO) E4 gene is the most potent genetic risk factor identified to date for late-onset AD. We will determine the impact of mitochondrial lipidomic dynamics and its interaction with different APOE isoforms on brain aging and AD progression. We expect this person will be trained on how to use different wet lab techniques including but not limited to liquid chromatography and mass spectrometry. Over time, this person is expected to develop independence in carry out own projects. This person will be part of team that develop assays to characterize lipids and lipoproteins.
Responsibilities
80% Research Activities
o Assist in designing research projects; independently plan and perform complex, multi-step experimental analyses; record all experimental protocols and data; organize and interpret experimental results.
o Perform experiments and analyze experimental samples. Generate sample/control analysis reports. Responsible for generating, recording, and analyzing data.
o Perform everyday tasks such as laboratory cleanup (using aseptic technique), replenishing supplies as needed, remove hazardous and chemical waste.
o Organize and set up equipment for research projects.
20% Administrative Lab Tasks
o Manage lab inventory and day to day orders
o Maintain biosafety procedures and administrative records, laboratory paperwork
o Assist with writing institutional protocols and manuscripts
All required qualifications must be documented on application materials.
Required Qualifications:
BS/BA in chemistry, biochemistry, or a related science field, and one year of relevant experience or a combination of education and experience to equal five years.
Experience managing datasets and preparing analysis
Excellent organization and attention to detail.
Excellent communication skills â" verbal and written.
Preferred Qualifications:
Research experience in a wet lab
Experience with liquid chromatography and mass spectrometry
Minneapolis, MN
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