Associate Principle Scientist - Veterinarian - Military Veterans
at Merck & Company
Job Description
Position Title
Principal Scientist, Computational Chemistry , West Point
Position Description
We are seeking a creative, self-motivated computational chemist with exceptional interpersonal and problem-solving skills to join the Modeling and Informatics team in West Point, PA, US .
M&I is a diverse and inclusive team of approximately 50 computational chemists and informaticians, who employ state of the art capabilities to drive drug design. We are an integral arm of both discovery and process chemistry and collaborate seamlessly with teams across the globe to innovate and invent better molecules faster . We are looking for a strategic thinker and accomplished computational drug hunter to take on a position that carries significant influence across our Company chemistry from target identification through delivery of clinical candidates in our Infectious Disease, Vaccine and Neuroscience portfolios .
Key responsibilities will include:
Scientific Innovation:
- Design and optimization of drug candidates using advanced computational techniques as a member of discovery teams
- Functioning as a subject matter champion for ligand - and structure - based drug design across discovery teams
- C ontributing to the continued growth and development of both modeling and chemistry colleagues as a mentor and influencer
- Advancing our modeling capabilities through invention and implementation of novel methodology as necessary to drive impact
Building Relationships:
- M entorship and scientific development of M&I staff both locally and across our network
- Building fruitful collaborations with stakeholders across medicinal chemistry, pharmacokinetics & pharmacodynamics, quantitative biosciences, and therapeutic area biology
- Trusted partner for Discovery Chemistry in West Point
- Identifying computational chemistry needs and opportunities across two broad portfolios for neuroscience and infectious disease at our West Point Chemistry hub in Pennsylvania.
Strategy:
- Leading specific strategic initiatives to enable our future vision for Modeling and Informatics in c hemistry
- Enabling a design-driven and predict-first culture throughout our Company Chemistry
- Contributing to our Company's overarching drug discovery strategy
We recognize that the diversity in our team is our strength and are committed to creating an inclusive environment for all employees. Successful candidates must demonstrate inclusive behaviors in working with a diverse group of scientists to drive our core mission.
Because we believe our best collaboration opportunities occur in a face-to-face context, this position will be in person, on site in West Point, PA.
Position Qualifications :
Education Minimum Requirement:
Ph.D. or M.S. degree in chemistry, biochemistry, biophysics, or equivalent with a computational emphasis .
Required Experience and Skills:
- 8 years of relevant professional experience ( i.e., Pharma, Biotech or equivalent) with a Ph.D., or 1 0 years with a M.S . degree.
- Proficiency in general molecular modeling techniques (docking, molecular simulation, homology modeling, quantum mechanics, QSAR / machine learning, ligand- and structure-based design) with modern software packages ( e.g. Schrodinger, OpenEye, CCG)
- Evidence of creative application of computational approaches to solve problems of pharmaceutical interest
- Exceptional oral and written communication skills, with a recognized ability to positively and impactfully influence team decisions
- Ability to communicate, collaborate and deliver results in a fast-paced, global environment and to manage multiple priorities simultaneously
- Ability to see the ' big picture ', and to identify opportunities for impact now and in the future
- Ability to lead strategic scientific initiatives relevant to drug discovery
- Passion for mentoring and coaching scientific peers
Preferred Experience and Skills:
- Skilled in scientific programming ( e.g. Python, Pipeline Pilot) and data analytics ( e.g. Spotfire) and democratizing coding and workflows
- People management experience
NOTICE FOR INTERNAL APPLICANTS
In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.
If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.
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U.S. Hybrid Work Model
Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as "remote".
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Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.
Employee Status:
Regular
Relocation:
Domestic
VISA Sponsorship:
No
Travel Requirements:
10%
Flexible Work Arrangements:
Not Applicable
Shift:
Not Indicated
Valid Driving License:
No
Hazardous Material(s):
N/A
Required Skills:
Chemistry, Computational Chemistry, Computer Aided Drug Design, Drug Design, High Performance Computing (HPC), Machine Learning, Molecular Dynamics (MD), Molecular Modeling, Problem Solving, Scientific Modeling, Structure Activity Relationship, Structure Based Drug Design, Teamwork
Preferred Skills:
Cheminformatics, Data Science, Informatics
Job Posting End Date:
12/20/2024
*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.
Philadelphia, PA
Today's Merck is a global healthcare leader working to help the world be well. Merck is known as MSD outside the United States and Canada. Through our prescription medicines, vaccines, biologic therapies, and consumer care and animal health products, we work with customers and operate in more than 140 countries to deliver innovative health solutions. We also demonstrate our commitment to increasing access to healthcare through far-reaching policies, programs and partnerships. For more information, visit www.merck.com.